Job Description
General/Position Summary
The Global Medical Affairs Science Associate Director has a leading role in Global Medical Affairs, working on global activities for the Povetacicept Programs. Povetacicept is an enhanced, dual BAFF/APRIL inhibitor in pivotal development for the treatment of both IgA Nephropathy (IgAN) and primary Membranous Nephropathy (pMN) that has best-in-class and pipeline-in-a-product potential. Key responsibilities include, but are not limited to, supporting Medical Plan development, supporting creation and deployment of medical content and materials such as slide decks, FAQs and external facing materials, and congress planning. The role requires collaboration with cross-functional business partners, including regional medical teams, health economics and outcomes research (HEOR), real world evidence (RWE), and commercial functions. This role may support execution of the publication plan. This role reports to the disease area Global Medical Lead and is a core member of the disease area Global Medical Affairs Team.
Key Duties & Responsibilities
- Execute the Global Medical Plan in collaboration with regional disease area teams and other internal stakeholders across Vertex.
- Creates or works closely with the Medical Director/Senior Director to create medically accurate, compliant and strategically aligned communication guidance on internal and external evidence for Medical Affairs
- Contributes to the development of global scientific platforms and lexicon for the development of scientific communications, training and core global materials (e.g., congress plans)
- Represents Vertex at scientific and medical forums, including medical education forums, scientific societies, and congresses.
- As necessary, engage with leading global key thought leaders (KTL), e.g., through participation in advisory boards or scientific engagement, to gain understanding of the therapeutic area
- Leads or supports the integration of scientific literature, society guidelines and competitive landscape into strategic publication planning
- Performs medical review of assigned brand-related content
- Supports Access, Patient Advocacy, Policy, and Corporate Communications teams with medical/scientific expertise and materials review
Required Education Level / Required Experience
- Advanced degree (Masters, PharmD. and/or Ph.D.) or equivalent highly relevant experience
- Typically requires 8 years of experience or the equivalent combination of education and experience
- It is preferred to have 3 or more years of relevant experience in medical affairs, scientific communications, or clinical development in either global or local/regional roles
Required Knowledge/Skills
- Demonstrated leadership and expertise in scientific communication frameworks, publication process and material development.
- Excellent medical/scientific knowledge of the disease area with outstanding oral and written communication skills.
- Identifies and defines problems and develops solutions using in-depth analysis with interpretive thinking. Negotiates effectively.
- Demonstrates strong business acumen with knowledge of cross-functional interdependencies of the drug development lifecycle.
- Proven leadership capabilities, ability to work within complex matrixes and without functional authority.
- Compliance experience and in-depth knowledge of relevant (area-specific) legislation or regulatory guidance governing the provision of medical information and appliable data privacy legislation.
- Actively foster strong working relationships with key influential stakeholders inside and outside of Vertex.
Pay Range:
$156,000 - $234,000Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site EligibleFlex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com


