Job Description

Vertex is seeking a talented scientist to join the Analytical Development organization in Boston, MA. This individual will help advance transformative medicines by performing analytical chemistry activities through all stages of clinical development. This role is in the Liquid Chromatography Subject Matter Expert (SME) team, dedicated to small molecule and synthetic peptide/oligonucleotide LC method development for both drug substances and drug products. The successful candidate will lead LC method development activities for assigned projects, participate as a core member in cross-departmental program teams, and serve as a technical expert in the space of liquid chromatography.

This is an onsite position.

Key Duties and Responsibilities:

• Develop analytical methods on HPLC/UHPLC with various detection systems (UV, QDa, CAD, etc.) for small molecules and synthetic peptides/oligonucleotides
• Conduct experiments independently following established methodology, procedures, and SOPs
• Exercise solid judgment to prioritize studies while considering feasibility, timelines, and project impact
• Independently prepare presentations and presents experimental conclusions at internal or external meetings
• Work collaboratively, cross-functionally, and within the team to achieve program goals
• Author and review method documents, analytical study protocols, and reports
• Maintain accurate notebook entries and adhere to governing SOPs
• Perform data verification/review of peer notebooks

Knowledge and skills:

• Design and execution of complex, challenging experiments
• Technical expertise in analytical techniques that include HPLC, UHPLC, IC, or LC-MS
• Demonstrated written and verbal communication skills especially in peer-directed presentations and report writing
• Experience in HPLC/UHPLC method development
• Advanced troubleshooting skills and problem-solving capabilities
• Strong analytical data assessment, review, and interpretation skills
• Ability to work in a fast-paced environment, managing priorities, and maintaining timelines

Education and Experience:

• Ph.D. (or equivalent degree) and 0-3 years of relevant post-doctoral employment experience in analytical chemistry or the life/physical sciences
• Masters Degree (or equivalent degree) and 3+ years of relevant employment experience, or
• Bachelors Degree (or equivalent degree) and 6+ years of relevant employment experience

Pay Range:

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com