Biogen
Scientist, DMPK - Bioanalytical
Cambridge, MA
Aug 22, 2025
Full-time
Full Job Description

Biogen is seeking a highly motivated scientist with excellent knowledge and experience in LC-MS/MS bioanalysis to join the Drug Metabolism and Pharmacokinetics (DMPK) department. The candidate will be responsible for bioanalytical support of discovery and development programs, including small molecule compounds and oligonucleotides (ASO, siRNA etc.). The candidate should be able to effectively manage and prioritize multiple projects to ensure timely support of the projects. Excellent communication and interpersonal skills are required, along with scientific thinking and problem-solving skills.

What You'll Do

  • Develop new bioanalytical methods for quantification of small molecule compounds and oligonucleotides (ASO, siRNA, oligonucleotide conjugates etc.) in biological matrices.
  • Analyze biological samples (plasma, CSF, tissue etc.) and timely deliver high quality bioanalytical data to support non-clinical and possible clinical studies.
  • Oversee non-GLP and GLP bioanalytical activities at CROs. Provide scientific guidance on method transfer/development, qualification/validation, and sample analysis at CROs.
  • Write and review study protocols and bioanalytical reports that are suitable for inclusion in registration dossiers.
  • Manage multiple projects within timelines according to high scientific and ethical standards.
  • Evaluate and implement new bioanalytical technologies for solving DMPK challenges or project needs.
  • Publish scientific papers and present at external scientific meetings.

Who You Are

You love bioanalysis and are passionate about applying bioanalysis to impact drug discovery and development. You love learning new technological skills and working through collaboration.

Required Skills

  • Ph.D. in analytical chemistry, biochemistry, or related discipline with 0-3+ years relevant industry experience.
  • In-depth knowledge and extensive experience with LC-MS/MS bioanalysis of small molecule compounds are required. Experience with other modalities such as oligonucleotides and proteins is desired.
  • Capable of performing bioanalysis and solving bioanalytical technical problems.
  • Familiar with bioanalytical method validation regulatory guidance and GLP regulations.
  • Understanding of pharmacokinetics and drug metabolism principles.
  • Excellent communication skills
  • Strong records of scientific publications
  • Ability to work independently in a fast-paced environment, as well as in a team setting.

Preferred Skills

  • Experience in ligand binding assays or qPCR assays is a plus.
  • Experience in regulated bioanalysis and GLP studies is preferred.


Job Level: Professional


Additional Information

The base compensation range for this role is: $114,000.00-$149,000.00


Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees' and their families physical, financial, emotional, and social well-being; including, but not limited to:

  • Medical, Dental, Vision, & Life insurances
  • Fitness & Wellness programs including a fitness reimbursement
  • Short- and Long-Term Disability insurance
  • A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
  • Up to 12 company paid holidays + 3 paid days off for Personal Significance
  • 80 hours of sick time per calendar year
  • Paid Maternity and Parental Leave benefit
  • 401(k) program participation with company matched contributions
  • Employee stock purchase plan
  • Tuition reimbursement of up to $10,000 per calendar year
  • Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired.Read onto learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

PDN-9fb12620-08d2-475a-8287-b3dacde2dd13
Job Information
Job Category:
Pharmaceutical
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Scientist, DMPK - Bioanalytical
Biogen
Cambridge, MA
Aug 22, 2025
Full-time
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