Job Description

Boston Pharmacokinetics, Dynamics, Metabolism and Bioanalytics - R2 Scientist

At our Company, we are inspired by the belief that a research-driven enterprise dedicated to scientific excellence can create medicines that save and improve lives.Every employee is building on our proudlegacy of scientific breakthrough.Our ability to impact the lives of patients worldwide depends on the integrity, creativity, humility and scientific acumen of our team.We are creating a diverse organization that is inspired by invention and founded on a culture of respect and collaboration.At our Research & Development Division Labs Boston, you'll have the opportunity to expand your knowledge and skills through collaboration with talented and dedicated colleagues while advancing your career.

The Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) group is seeking a dynamic, strategic thinking and collaborative Scientist to contribute to our Company's drug discovery and early clinical development efforts, with a focus on lab-based bioanalytical efforts for small molecules and peptides. This position will be based at our research labs in Boston, MA. Experience utilizing liquid-chromatography / mass spectrometry platforms to quantify small molecules and/or peptides from various in vitro and in vivo matrices is required. The ability to develop new bioanalytical methods, efficiently utilize data processing platforms and perform basic instrument maintenance is a plus. The position will allow for regular interaction with multi-disciplinary discovery project teams and subject matter experts from other functions within our Research & Development Division. The ideal candidate will possess the ability to innovate, independently execute and be fully accountable for their scientific deliverables. The candidate will have the opportunity to present their work at departmental meetings as well as promote our Company science through publications and external presentations.

In this exciting position, your primary roles will include:

• Utilize state-of-the-art liquid chromatography/mass spectrometry approaches to quantitate drug levels in various in vitro and in vivo matrices in support of PK and PK/PD efforts

• Analyze, review and utilize quantitative data to estimate pharmacokinetic parameters in support of multiple programs across various therapeutic areas

• Close collaboration with PDMB subject-matter experts in Boston (MA), South San Francisco (CA) and West Point (PA) aimed at efficiently supporting a dynamic and fast-paced research portfolio

Education Minimum Requirement

• Bachelor's degree with 3+ years relevant laboratory experience or MS degree in biochemistry, chemistry, pharmacology, pharmaceutical sciences, biomedical engineering or related field.

Required Experience and Skills

• Demonstrated experience utilizing liquid-chromatography / mass spectrometry (LC/MS) platforms to quantify small molecules and/or peptides from various in vitro and in vivo matrices

• Working knowledge of traditional bioanalytical instrumentation and techniques (primarily LC/MS), including method development, optimization and general maintenance

• Experience preparing samples from various in vitro and in vivo matrices for bioanalytical characterization including, but not limited to, protein precipitation, liquid/liquid extraction and solid-phase extraction techniques.

• Strong interpersonal, communication, problem solving and collaborative qualities to deliver high quality results in a fast-paced environment

Preferred Experience and Skills

• Ability to design, interpret and troubleshoot experiments aimed at addressing complex questions

• Familiarity with electronic laboratory notebooks, Watson LIMS and related record-keeping approaches

• Experience working within a research-driven pharmaceutical company

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

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US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

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Requisition ID:R348103