Biogen
Sr. Scientist, Medicinal Chemistry
Cambridge, MA
Jun 6, 2025
Full-time
Full Job Description

About This Role

We are looking for a medicinal chemist who can provide significant contributions to medicinal chemistry strategy and who will have a significant laboratory presence that is focused on enabling critical chemistry for Small Molecule project advancement. The ideal candidate will leverage their deep understanding of medicinal and synthetic chemistry and to help deliver high quality Small Molecule clinical candidates as part of Biogen's research portfolio.

What You'll Do

  • Leverage your expertise in medicinal chemistry and organic synthesis to help deliver clinical candidates for high value Small Molecule programs
  • Collaborate with team members to build the strategy to iteratively identify/design analogs that advance the project (pharmacology, ADME, safety) via the application of structure-based, ligand-based, property-based, and efficiency-based design.
  • Work collaboratively with key functions such as DMPK, Biology, Chemical Biology and Proteomics, Bioassays and High Throughput Screens, and Physical Biochemistry to deliver optimal Small Molecule candidates.
  • Maintain a significant laboratory presence that is focused on identifying and enabling critical synthetic chemistry for advancing the project that can be used by chemistry CROs and the internal/external Biogen Parallel Medicinal Chemistry (library synthesis).
  • Maintain an understanding of cutting edge synthetic chemistry and how it can be applied to their own project and other projects in the department.
  • Leverage internal Synthesis Technologies resources such as High Throughput Experimentation, Parallel Medicinal Chemistry, and Purification to drive impactful synthesis strategies that advance their project.
  • Oversee external chemistry CROs to maximize the efficiency of compound synthesis and characterization.

Who You Are

You are a medicinal chemist with experience in an industrial setting along with a proven track record of impactful contributions on small molecule drug discovery programs. You enjoy working in cross-functional teams to advance compounds towards clinical candidate selection

Required Skills

  • Ph.D. in organic or medicinal chemistry with minimum of 3 years biopharmaceutical medicinal chemistry experience or M.S. with a minimum of 5 years biopharmaceutical medicinal chemistry experience
  • Demonstrated ability to influence project advancement.
  • Well-established track record of conducting innovative drug discovery research as evidenced through publications, patent applications, and presentations.
  • Demonstrated ability to work effectively in a high-paced, collaborative environment with an ability to share and receive constructive feedback.


Job Level: Professional


Additional Information

The base compensation range for this role is: $114,000.00-$149,000.00


Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees' and their families physical, financial, emotional, and social well-being; including, but not limited to:

  • Medical, Dental, Vision, & Life insurances
  • Fitness & Wellness programs including a fitness reimbursement
  • Short- and Long-Term Disability insurance
  • A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
  • Up to 12 company paid holidays + 3 paid days off for Personal Significance
  • 80 hours of sick time per calendar year
  • Paid Maternity and Parental Leave benefit
  • 401(k) program participation with company matched contributions
  • Employee stock purchase plan
  • Tuition reimbursement of up to $10,000 per calendar year
  • Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired.Read onto learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

PDN-9f164222-e23d-4083-8f39-f0c39817ab0c
Job Information
Job Category:
Pharmaceutical
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Sr. Scientist, Medicinal Chemistry
Biogen
Cambridge, MA
Jun 6, 2025
Full-time
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