Job Description
Senior Principal Scientist, Precision Medicine, Immunology
Precision Medicine is an integral part of our Immunology Therapeutic Area. To support our growing Immunology pipeline across Gastroenterology, Rheumatology and Dermatology we are seeking an experienced experimental medicine leader in our newly created Precision Medicine and Diagnostics function. Reporting to the Associate Vice President ,Precision Medicine and Diagnostics, in this role, you will serve as the translational lead on late-stage immunology programs, driving the Precision Medicine objectives in alignment with clinical development plans. Collaborating with Discovery, Translational Medicine and Product Development Teams, you will be the authority in defining and interpreting the translational experiments and data generated respectively from our clinical trials, and understanding the potential clinical application of biomarkers/diagnostics arising from these.
Key Responsibilities
Work with the Associate Vice President Precision Medicine and Diagnostics/TA Vice President and cross-functional partners to define Precision Medicine strategy within the Immunology TA
Work closely with a cross-functional group of experts, including clinical directors, clinical trial operations, and biomarker operations teams as they key liaison to enable implementation of precision medicine strategy in clinical trials
Contribute to creation of translational plans for all programs within the Immunology TA, aligned with overall TA strategy and with relevant disease area and/or pathway strategies
Collaborate with discovery colleagues for programs in early stage to influence biomarker assessments and readouts to drive forward and reverse translation tied to Precision Medicine goals
Champion the use of new technologies and modalities to drive Precision Medicine vision
Support the development, approval and commercialization of diagnostics developed as companion or complementary
Serve as the key stakeholder engaging with external experts on drafting and reviewing concepts aligned with the Precision Medicine goals for relevant programs/assets
The Senior Principal Scientist is responsible for maintaining a strong scientific fund of knowledge by:
Maintaining awareness of scientific developments within one's area of expertise, in terms of new scientific findings, research methodologies
Attending appropriate scientific meetings to maintain one's competency and to maintain awareness of research activities in one's area of responsibility
To accomplish these goals, the Senior Principal Scientist may:
Author detailed development documents, presentations, budgets, and position papers for internal and external audiences
Collaborate with external experts/researchers around the world with a specific interest and expertise related to Precision Medicine
Travel on company business about twenty (20) percent of the time to manage future or ongoing clinical research projects.
Required Qualifications
PhD degree in Immunology required
Minimum of 8 years of experience in immunology translational research in a pharmaceutical and academic setting, with a focus on inflammatory and autoimmune diseases in Gastroenterology, Rheumatology, and Dermatology.
Strong knowledge of the pathogenesis of immune mediated disease and the application of cellular, molecular technologies and models to drive program decisions.
Detailed understanding of translational and clinical research methodology and biostatistics principles.
Prior experience in drafting regulatory documents and interactions with global regulatory agencies required
Self-driven leader willing to advance Precision Medicine in Immunology
Demonstrated ability to work in a highly matrixed environment
Preferred Qualifications:
People management experience
Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
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U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".
The salary range for this role is
$206,200.00 - $324,600.00This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.
You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.
San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only:We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
RegularRelocation:
DomesticVISA Sponsorship:
NoTravel Requirements:
10%Flexible Work Arrangements:
HybridShift:
Not IndicatedValid Driving License:
NoHazardous Material(s):
n/aRequired Skills:
Bioinformatics, Bioinformatics, Biomarker Research, Clinical Development, Clinical Immunology, Clinical Medicine, Clinical Research, Clinical Testing, Clinical Trial Management, Cross-Cultural Awareness, Cross-Functional Teamwork, Dermatology, Drug Development, Ethical Compliance, Ethical Standards, Immunoassays, Immunotherapy, Management Process, Medical Research, Mentorship, Parasitology, Patient Care, Professional Networking, Protocol Development, Regulatory Compliance {+ 4 more}Preferred Skills:
Job Posting End Date:
06/28/2025*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Requisition ID:R352481
